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Regular hexagons represent the most efficient geometric tessellation of a two-dimensional plane, minimizing perimeter length while maximizing interior area. This mathematical property makes hex grids standard across both molecular biology and tabletop wargaming.
Chemistry students use small 4 mm to 6 mm hex grids to rapidly draw skeletal structures, benzene rings, cycloalkanes, and Haworth carbohydrate projections with clean 120-degree bond angles.
In wargames (e.g., Battletech, hex-and-counter strategy) and D&D exploration, hex grids eliminate the diagonal movement distortion found in square Cartesian grids (where diagonal steps measure $\sqrt{2} \approx 1.414$ times farther). Every adjacent hex is equidistant from the center.